Polpharma Pharmaceutical Works - API Manufacturer

A key to success is a combination of in-house expertise and effective co-operation with scientific institutions and laboratories. To expand or complement our capabilities, we provide an extensive range of partnering projects.

List of reactions provided in-house or at partners:

• Regular organic chemistry processes (coupling, condensations, oxidations, reductions, solvolysis ect.)
• Chiral separations (diastereoisomeric crystallizations)
• Stereoselective synthesis
• Regioselective synthesis
• Carbohydrate chemistry (glycosylations, functional groups transformations)
• Amino acids and peptide chemistry (solution and solid-phase synthesis)
• Phosphorous chemistry (eg. bisphosphonates)
• Polymorphism
• Catalysis (phase transfer catalysis, heterogeneous and homogenous)
• Sodium amide at large scale
• Grignard reactions at large scale
• Catalytic hydrogenation at large scale
• Effective process optimizations